Production Pharmacist

About the role

A client in the pharmaceutical manufacturing industry in Gauteng, South Africa, is looking for experienced Production Pharmacists to oversee pharmaceutical and technical aspects of manufacturing operations. Products must be manufactured, packaged and documented in line with Good Manufacturing Practice (GMP), SAHPRA requirements, approved procedures and quality standards.

Key responsibilities

• Oversee pharmaceutical manufacturing and packaging operations, ensuring compliance with cGMP, SAHPRA requirements, approved SOPs and product specifications.
• Monitor production activities, line clearance, material segregation, equipment verification and manufacturing conditions.
• Review batch manufacturing records, material reconciliations and production documentation for accuracy, completeness and data integrity.
• Draft, review, update and implement SOPs, work instructions, batch records and other GMP-controlled documentation.
• Investigate production deviations, non-conformances, OOS/OOT results and quality incidents, including root cause analysis and CAPA implementation.
• Support process validation, cleaning validation, equipment qualification, risk assessments and change control.
• Identify and implement continuous improvement initiatives.
• Deliver GMP, SOP, manufacturing process and data integrity training.
• Support internal, customer and regulatory audits, including SAHPRA inspections, and keep production areas inspection-ready and compliant with occupational health, safety and environmental requirements.

Required profile

• Bachelor of Pharmacy (BPharm).
• Registration with the SAPC.
• 3-5 years of pharmaceutical manufacturing experience.
• Experience in solid dosage, liquids, creams or sterile manufacturing environments.
• Experience with batch documentation, deviation investigations, CAPA management, root cause analysis and process validation.

Required skills

• GMP systems, regulatory inspections, SOP development and document control.
• Knowledge of SAHPRA regulations, PIC/S GMP guidelines and pharmaceutical manufacturing processes.
• Risk management, data integrity and production quality standards.
• Leadership, problem-solving, communication and decision-making skills; quality-driven and detail-oriented.