Senior Principal Biostatistician

About the role

ICON is a global healthcare intelligence and clinical research organisation. As a Senior Principal Biostatistician, you will lead statistical methodologies and contribute to the design and analysis of clinical studies, ensuring high standards of data integrity and regulatory compliance.

Key responsibilities

• Oversee biostatistics workstreams so that deliverables meet quality and timeline expectations.
• Design and implement statistical analysis plans for clinical trials aligned with study objectives and regulatory guidelines.
• Oversee the statistical analysis of clinical data and provide insights and interpretations for decision-making and reporting.
• Collaborate with clinical, regulatory and data management teams for integrated study execution.
• Mentor junior statisticians and train them on statistical methodologies and software.
• Contribute to regulatory submissions and publications, ensuring statistical rigor and transparency.
• Stay up to date on industry trends and statistical methodology advances.
• Take part in protocol development and give input on endpoints and statistical considerations.

Required profile

• Master's degree or Ph.D. in Biostatistics, Statistics or a related field.
• Extensive biostatistics experience in the pharmaceutical or biotech industry, especially clinical trial design and analysis.
• Solid experience managing competing priorities and developing a team.
• Demonstrated leadership, with mentoring and guiding teams.
• Ability to interpret complex data and communicate statistical concepts to non-statistical audiences.
• Detail-oriented, able to manage multiple projects and meet deadlines in a fast-paced environment.

Required skills

• Strong knowledge of statistical software such as SAS and R.
• Proficiency in programming for data analysis.

What we offer

• Competitive base salary and performance-related incentives.
• Health and wellbeing programmes, including medical, dental and vision coverage where applicable.
• Retirement and pension plans, life assurance and disability coverage.
• Employee assistance programmes and learning and development opportunities.